COMPARATIVE EFFICACY OF LASOTA, B1 AND Po MUKTESWAR STRAIN VACCINES FOR NEWCASTLE DISEASE VIRUS (NDV) IN POULTRY

Abstract

The control of ND relies on the use of safe and effective vaccines. Live vaccines prepared with lentogenic strains of NDV are now more commonly used in broilers and layers than vaccines prepared from chemically inactivated strains of NDV, mixed with adjuvant. This is because live freeze-dried vaccines can be produced on a large scale at a relatively low cost. The vaccines are easy to administer on a large scale, and rapidly stimulate humoral, cell-mediated and mucosal surface immunity. From this experimental work the principal objectives of the present investigation it may be stated that production of HI-antibody was higher in birds of group A (512) vaccinated with ND LaSota®, compared to those of group B vaccinated with RDV (Mukteswar strain);256, group C vaccinated with ND B1 (B1 strain) Hitchner®;2.78 at 6 weeks after vaccination. Thus, the ND Lasota® was found to be superior to some extent than . ND B1, Hitchner. However, as regards vaccination of chicks against NDV in earlier days the use of lentogenic strains are recommended although it should be kept in mind that vaccination with LaSota strains would cause considerably greater problems in young susceptable birds than Hitchner B, strain and even through LaSota induces a stronger immune response (OIE Manual, 4" Edition, 2008).