COMPARATIVE EFFICACY OF NEGUVON AND NEEM (Azadirachta indica) LEAVES EXTRACT AGAINST STEPHANOFILARIASIS IN CATTLE IN DINAJPUR DISTRICT

Abstract

Stephanofilariasis one of the most problematic parasitic diseases caused by Stephanofilaria assamensis is endemic to Bangladesh. The disease could neither be fully controlled nor eradicated from these regions in spite of various attempts. The present study was conducted to find out the prevalence of the disease in the endemic areas, its economic impact and suitable measures for its eradication. The incidence rate was more in older animals. The direct and indirect economic losses to farmers by way of loss of draught days, delayed puberty, lower lactation yields and prolonged intercalving period were enormous. The control and eradication of Stephanofilariasis in bovines could be successfully achieved especially by targeting the life cycle of the biological vector (Musca conducens), the intermediate host. Improvement in general cleanliness and hygiene to reduce the fly population. An experiment was carried out in nearby Villages and also in the Laboratory in the Department of Physiology and Pharmacology, Hajee Mohammad Danesh Science and Technology University, Dinajpur during the period from July-December/ 2012. The Neguvon powder and the extract of Neem (Azadirachta indica) leaves were screened for assessment their comparative efficacy against humpsore in cattle. Among these, neem leaves extract were used topically to cover the affected area and Neguvon powder was applied topically twice daily to the cattle. 10gm Neguvon powder was mixed with 90gm Vaseline for 28days. Efficacy was recorded as compared to control. Extract of neem leaves showed gradual increase of efficacy up to day29th of treatment. Among two drugs Neguvon show better performance than neem leaves extract. But Neem leaves extract shows no side effect on body of cattle.