dc.contributor.advisor | Dr. Md. Nazrul Islam | |
dc.contributor.author | MURMU, ROZINA | |
dc.date.accessioned | 2022-04-23T03:58:11Z | |
dc.date.available | 2022-04-23T03:58:11Z | |
dc.date.issued | 2010-08 | |
dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/541 | |
dc.description | Infectious bursal disease (IBD) or Gumboro disease is an acute, highly contagious viral
disease of young chickens characterized mainly by severe lesions in the bursa of
Fabricius (BF) followed by immunosuppression (Fadley et al.,1976; Rosenberger and
Gelb, 1978; Saif, 1994; Lukert and Saif, 1997). It is a major poultry pathogen in the
poultry industry (Hein et al., 2002). Infectious bursal disease virus (IBDV), the
oetiological agent of Gumboro disease, belonging to the genus Birnavirus (Murphy et
al. 1995), sub-genus Avibirnavirus (Pringle, 1998), family Birnaviridae (Dobos et al.,
1979; Brown, 1986). IBD is economically important for the poultry industry in function
of the immune depression that it causes (Moraes et al., 2004). One of the significant
components of the control of the disease is its vaccination which if improved may help
in lowering the incidence of the disease in poultry (Zaheer et al., 2003). IBD has been
widely studied mainly for two reasons: | en_US |
dc.description.abstract | A modified form of Intermediate plus of Infectious Bursal Disease Vaccine
(HIPRAGUMBORO~-GM97) prepared from the GM97 strain of Infectious Bursal Disease
virus was tested for its pathogenicity in commercial chickens. A total of 500 unvaccinated
Cobb-500 commercial chicks, raised in relative isolation from day old. 21 chicks were
collected from experimental farm at Day: (D1), Diz, Dis, Diz, Dao, Dz3 and Dz. respectively
three birds were collected from each respective day. Vaccine was administered at ocular
route at Day1 and boosting was done at Dayi7 with drinking water. A typically affected
flock was included in this study for the comparison of the study. Clinical signs were
observed. All the sampled birds were subjected to detailed necropsy. The visible gross
morbid lesions, Bursa/Body weight ratios was recorded. The bursae were collected,
preserved at 10% formalin, processed, sectioned and stained for histopathology including
determination of bursal lesion scores. Data's were analyzed statistically. | en_US |
dc.language.iso | en | en_US |
dc.publisher | HAJEE MOHAMMAD DANESH SCIENCE AND TECHNOLOGY UNIVERSITY, DINAJPUR. | en_US |
dc.subject | COMMERCIAL CHICKENS | en_US |
dc.subject | Geographical distribution and prevalence of IBD | en_US |
dc.subject | Sources and transmission of infection | en_US |
dc.title | PATHOLOGICAL EVALUATION OF GUMBORO VACCINE PREPARED FROM FREEZE-DRIED CULTURE OF THE “LIVE GUMBORO VIRUS GM97 STRAIN” (HIPRA GUMBORO® - GM97) INCOMMERCIAL CHICKENS | en_US |
dc.type | Thesis | en_US |