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dc.contributor.advisorDr. Md. Nazrul Islam
dc.contributor.authorMURMU, ROZINA
dc.date.accessioned2022-04-23T03:58:11Z
dc.date.available2022-04-23T03:58:11Z
dc.date.issued2010-08
dc.identifier.urihttp://localhost:8080/xmlui/handle/123456789/541
dc.descriptionInfectious bursal disease (IBD) or Gumboro disease is an acute, highly contagious viral disease of young chickens characterized mainly by severe lesions in the bursa of Fabricius (BF) followed by immunosuppression (Fadley et al.,1976; Rosenberger and Gelb, 1978; Saif, 1994; Lukert and Saif, 1997). It is a major poultry pathogen in the poultry industry (Hein et al., 2002). Infectious bursal disease virus (IBDV), the oetiological agent of Gumboro disease, belonging to the genus Birnavirus (Murphy et al. 1995), sub-genus Avibirnavirus (Pringle, 1998), family Birnaviridae (Dobos et al., 1979; Brown, 1986). IBD is economically important for the poultry industry in function of the immune depression that it causes (Moraes et al., 2004). One of the significant components of the control of the disease is its vaccination which if improved may help in lowering the incidence of the disease in poultry (Zaheer et al., 2003). IBD has been widely studied mainly for two reasons:en_US
dc.description.abstractA modified form of Intermediate plus of Infectious Bursal Disease Vaccine (HIPRAGUMBORO~-GM97) prepared from the GM97 strain of Infectious Bursal Disease virus was tested for its pathogenicity in commercial chickens. A total of 500 unvaccinated Cobb-500 commercial chicks, raised in relative isolation from day old. 21 chicks were collected from experimental farm at Day: (D1), Diz, Dis, Diz, Dao, Dz3 and Dz. respectively three birds were collected from each respective day. Vaccine was administered at ocular route at Day1 and boosting was done at Dayi7 with drinking water. A typically affected flock was included in this study for the comparison of the study. Clinical signs were observed. All the sampled birds were subjected to detailed necropsy. The visible gross morbid lesions, Bursa/Body weight ratios was recorded. The bursae were collected, preserved at 10% formalin, processed, sectioned and stained for histopathology including determination of bursal lesion scores. Data's were analyzed statistically.en_US
dc.language.isoenen_US
dc.publisherHAJEE MOHAMMAD DANESH SCIENCE AND TECHNOLOGY UNIVERSITY, DINAJPUR.en_US
dc.subjectCOMMERCIAL CHICKENSen_US
dc.subjectGeographical distribution and prevalence of IBDen_US
dc.subjectSources and transmission of infectionen_US
dc.titlePATHOLOGICAL EVALUATION OF GUMBORO VACCINE PREPARED FROM FREEZE-DRIED CULTURE OF THE “LIVE GUMBORO VIRUS GM97 STRAIN” (HIPRA GUMBORO® - GM97) INCOMMERCIAL CHICKENSen_US
dc.typeThesisen_US


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