DETERMINATION OF EFFICACY OF DIFFERENT NEWCASTLE DISEASE VACCINE (NDV) USED IN BROILER CHICKEN

Abstract

The control of ND relies on the use of safe and effective vaccines. Live vaccines prepared with lentogenic strains of NDV are now more commonly used in broilers than vaccines prepared from chemically inactivated strains of NDV, mixed with adjuvant (Biggs ef al., 1988; Alexander, 1991). This is because live freeze-dried vaccines can be produced on a large scale at a relatively low cost. The vaccines are easy to administer on a large scale, and rapidly stimulate humoral, cellmediated and mucosal surface immunity. From this experimental work the principal objectives of the present investigation it may be stated that production of HI-antibody was higher in birds of group D vaccinated with Cevac Vitapest-L* compared to those of group A vaccinated with Medivac NDLaSota”, group B vaccinated with BCRDV(R) and group C vaccinated with Izovac. B, Hitchner”. Thus, the Cevac Vitapest-L" was found to be superior to some extent than Medivac ND-LaSota, BCRDV", Izovac B, Hitchnert. However, as regards vaccination of chicks against NDV in earlier days the use of lentogenic strains are recommended although it should be kept in mind that vaccination with LaSota strains would cause considerately greater problems in young susceptable birds than Hitchner B, strain and even through LaSota induces a stronger immune response (OIE Manual, 4h Edition, 2000).