| dc.contributor.advisor | Dr. Md. Fazlul Hoque | |
| dc.contributor.author | UDDIN, MD.KARIM | |
| dc.date.accessioned | 2022-04-21T05:57:44Z | |
| dc.date.available | 2022-04-21T05:57:44Z | |
| dc.date.issued | 2013-12 | |
| dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/383 | |
| dc.description | Influenza A virus is the member of the Orthomyxoviridae family. The virus is a
negative-sense single-stranded RNA virus with a segmented genome (7 to 8
separated segments), which encodes for 11 different viral proteins (Olsen ef al.,
2006; Lamb et al., 2007). Influenza type A virus is divided into subtypes based on
two antigenic proteins on the surface of the virus, the hemagglutinin (HA) and
the neuraminidase (NA).Both proteins are embedded into the lipid envelope of
the virus, form characteristic spikes visible under electron microscopy, and are
responsible for the viral attachment and the viral release from the host cells
(Skehel et a/., 2000). In addition, HA protein is considered the most important
determinant of host specificity. There are 16 different HA subtypes and 9
different NA subtypes and the combination of the HA and the NA in a virus
defines the subtypes (Nicholls et al., 2008). Pigs are susceptible to infection
with a wide range of influenza type A viruses. This is because cells of pig
respiratory epithelia express receptors for both mammalian and avian influenza
viruses (N-acetilneuromaminic acid- 2,3 galactose and N-acetilneuromaminic acid2,6 galactose linkages). The continued replication of avian and human influenza
viruses in pigs has led to the emergence of new reassortants by antigenic shift or
to antigenic changes in the HA protein of swine influenza strains by antigenic
drift (Ito et al., 1998). | en_US |
| dc.description.abstract | The serological investigation was carried out to determine the seroprevalence
of influenza A in swine population Rangamati and Khagracchari districts of
Bangladesh by using indirect ELISA and Identification of significant risk
factors associated with Influenza A virus Epidemiology. A total of 90 sera
samples of swines from different areas of Rangamati and Khagracchari
districts of Bangladesh from January 2013 to December 2013.All sera
samples were examined for the detection of antibodies of influenza A virus
by indirect enzyme linked immunosorbant assay using commercially
available kits. The seroprevalence of influenza A was 15% in Rangamati
district, 10% in Khagracchari district. The overall seroprevalence between
the aforesaid districts was recorded 12.22%. The investigation exhibit
highest seroprevalence was found in Rangamati district (15%) and the
lowest seroprevalence was (10%) found in Khagracchari district. The
seroprevalence rate of influenza A was found 14.29% in male pigs and
9-76% in female pigs. The seroprevalence of influenza A was studied
based on age and It was observed that 11-5% seroprevalence was found in
grower pigs, 12:°5% in fattening pigs and12:5% in adult pigs. The
investigation revealed that the highest (12:-5%) prevalence was found in
fattening and adult pigs and the lowest prevalence was found in grower
pigs | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | HAJEE MOHAMMAD DANESH SCIENCE AND TECHNOLOGY UNIVERSITY, DINAJPUR. | en_US |
| dc.subject | IN SWINE POPULATION | en_US |
| dc.subject | Geographic Distribution | en_US |
| dc.subject | PATHOGENESIS AND CLINICAL SIGNS | en_US |
| dc.title | SEROPREVALENCE OF INFLUENZA A IN SWINE POPULATION OF RANGAMATI AND KHAGRACCHARI DISTRICTS | en_US |
| dc.type | Thesis | en_US |
