BACTERIOLOGICAL PROFILE AND ANTIBIOTIC SENSITIVITY PATTERN IN PATIENTS WITH URINARY TRACT INFECTION AT MISSIONARY HOSPITAL IN DINAJPUR

Abstract

Urinary Tract Infections (UTIs) is an infection caused by the presence and growth of pathogen anywhere in the urinary tract including a kidney, ureter, bladder, and urethra. It is one of the most common bacterial infections in women, and 50% to 60% of adult women experience a UTI during their lifetime. In women, the ascent of a number of organisms into the bladder is easier than in men because of the relatively short urethra and absence of bactericidal prostatic secretion. The infections cause a serious health problem affecting millions of people each year and considered among the most common infectious diseases affecting all age groups, from infants to the elderly and also the most common infections seen in hospitalized patients and the second most common, after respiratory tract infections, seen in the general population. A total of 40 samples were collected from different inpatients at missionary Hospital, the study was carried out during the period January 2019 to June 2020. The urine samples are collected and brought to the laboratory under the Department of Microbiology, Hajee Mohammad Danesh Science and Technology University, Dinajpur and subjected to different bacteriological profile tests for isolation and identification of bacteria based on Morphology, Staining, Culture and biochemical examinations and antibiogram study. Out of 40 clinical samples, 31(77.5%) samples were collected from female and 9(22.5%) were from male. Out of the culture positive samples, female patients were more (82.1%) than male patients (17.9%). Several other studies show similar findings. The high incidence in female is due to colonization with enteric bacteria due to short urethra. Most number of positive urine cultures (39.28%) was seen in age group 31- 40 years. Our study showed UTI is a common problem faced by clinicians in every part of the world irrespective of the age and sex. We discuss the relationship between age, sex, and pathogens isolated, antibiotic sensitivity pattern in UTI. The culture positive cases were 28 (70%) out of 40 cases which were enrolled in our study. al in their studies showed culture positive in 31% and 24.5% cases respectively. In another study, culture positive as low as 8.7%. The study revealed that the total prevalence bacteria were E. coli 12(44.9%), Staphylococcus spp 8(28.6%) and Klebsiella spp 5(17.9%). E. coli showed sensitivity to Gentamicin, Amikacin, and Ciprofloxacin respectively. Klebsiella spp showed sensitivity to Ciprofloxacin, Gentamicin and Amikacin.Staphylococcuss spp. showed to Chloramphenicol, Amikacin and Gentamicin