| dc.contributor.advisor | Dr. Md. Mahmudul Hasan | |
| dc.contributor.author | AKTER, SHEFALY | |
| dc.date.accessioned | 2022-05-15T06:34:55Z | |
| dc.date.available | 2022-05-15T06:34:55Z | |
| dc.date.issued | 2018-06 | |
| dc.identifier.uri | http://localhost:8080/xmlui/handle/123456789/1482 | |
| dc.description | A THESIS
BY
SHEFALY AKTER
Registration No.: 1605514
Session: 2016-2017
Semester: January-Jun, 2018
Submitted to the Department of Physiology & Pharmacology
Hajee Mohammad Danesh Science and Technology University, Dinajpur,
Bangladesh in partial fulfillment of the requirements
For the degree of
MASTER OF SCIENCE (MS)
IN
PHARMACOLOGY | en_US |
| dc.description.abstract | This study was undertaken to observe the effects of spirulina (Spirulina platensis) and
riboflavin in hematological and biochemical parameters against arsenic toxicity in Long
Evans rat. Sixty male rats were taken to perform the study. Experimental rats were divided
into five equal groups. Each group consists of 12 rats. Animals of T0 group were given
normal feed and water and kept as control. Rats of T1, were given arsenic trioxide @ 100
mg/L drinking water orally. Rats of group T2 were given arsenic trioxide @ 100 mg/L
drinking water and with spirulina @ 1 gm/kg feed. Group T3 were given arsenic trioxide @
100 mg/L with riboflavin @ 10mg /kg body weight. Group T4were given arsenic trioxide and
spirulina and riboflavin with same dose up to 45 days respectively. Four rats from each group
(T0, T1, T2, T3 and T4) were sacrificed at 15 days interval to determine body weight,
hematological and biochemical parameters. Result showed that in group T1, body weight gain
was minimum, whereas in groupT2, T3 and T4 the body weight gain in rats were better.
Reduction of TEC, Hb values were significant (P<0.01) in T1 group. Whereas in rest groups
reduction of TEC, Hb were less than arsenic treated groups. The values of SGOT and SGPT
were significantly (P<0.01) decreased in all group but in it is more effective in combined
group. In conclusion, spirulina and riboflavin has significant effect on hematological and
biochemical parameters and increase body weight. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | HAJEE MOHAMMOD DANESH SCIENCE AND TECHNOLOGY UNIVERSITY, DINAJPUR | en_US |
| dc.subject | SPIRULINA | en_US |
| dc.subject | D RIBOFLAVIN | en_US |
| dc.subject | ARSENIC TOXICITY | en_US |
| dc.title | EFFECT OF SPIRULINA (Spirulina platensis) AND RIBOFLAVIN AGAINST ARSENIC TOXICITY IN RAT | en_US |
| dc.type | Thesis | en_US |
