| dc.description.abstract | Chronic arsenic (As) toxicity is a severe disease in men and animals which occurs severely in
Bangladesh. As contamination in ground water used in drinking is the major concern because
arsenic is present in human and animal food chain. This work was done in quails with a view
to study the comparative efficacy of Spirulina (Spirulina platensis) and Garlic (Allium
sativum) for prevention of arsenic toxicity. Forty quails were used in this study and animals
were divided into control group (T0), Arsenic treated group (T1), Arsenic (As) plus Spirulina
treated group (T2) and Arsenic (As) plus Garlic treated group (T3). Each group consists of 10
quails. Quails of T0 group were given normal feed and water and kept as control. Quails of
T1, T2 and T3 were given 100 mg Arsenic (As) trioxide/L drinking water daily for 30 days. In
addition to arsenic (As) trioxide quails of group T2 and T3 were simultaneously fed with
Spirulina @ 1 gm/kg feed and T3 were simultaneously feed with Garlic @ 1gm /kg body
weight up to 30 days respectively. Five quails from each group (T0, T1, T2 and T3) were
sacrificed at 15 days interval in order to determine hematological parameters. Result showed
that in group T1, body weight gain was minimum, whereas in groupT2 and T3 the body weight
gain in quails were better. Reduction of TEC, Hb values were significant (P<0.01) in T1
group. Whereas in rest groups reduction of TEC, Hb were less than arsenic treated groups.
Noticeable change observed in liver and kindey of arsenic (As) treated group in compare to
control group in postmortem and histopathological changes. In conclusion, spirulina and
garlic have significant effect on body weight, hematological, postmortem and
histopathological changes. | en_US |
