EFFECT OF DIFFERENT DOSAGE OF DIETARY CADMIUM (Cd) ON BIOCHEMICAL AND MORPHOLOGICAL CHANGES IN DIFFERENT ORGANS OF COMMERCIAL QUAILa

Abstract

Poultry is the promising sector of Bangladesh which is one of the major protein sources for people in Bangladesh. Such beneficial promising sector may be the cause of public health hazard due to the anthropogenic heavy metal exposure & accumulation in poultry tissues. The present study was aimed to investigate the toxic effects of Cadmium (Cd) exposure in quail. For this purpose, a total number of 72 quail chicks (12 days old) were assigned in four dietary treatments with three replicates. Control group received only basal diet without any supplementation. The other groups T1, T2 and T3 received supplemented Cd with feed at a dose level of 0.2, 1 and 5mg/kg feed respectively. The body weight of each bird was weighed at 7 days interval and found significant variations among the groups. Decrease in weight gain is due to malabsorption of nutrients from direct toxic effects of Cd on the gastrointestinal tract or by inhibition of protein synthesis. Blood and tissue samples were collected on the 29th days of dietary treatment. Cd caused elevation of ALT (P<0.01) and decreased serum creatinine attributed to gross and histopathological changes in liver and kidney respectively. Histopathological lesions in liver included infiltration of reactive cells in central vein, hepatic vein and sinusoidal space in group T1 and T2 whereas group T3 showed highly necrosis of hepatocyte, picnotic nucleus and disarrangement of hepatic cord. In kidney, tubules were filled with reactive cells in all Cd treated groups while necrosis and disarrangement of tubules were found in groups fed Cd at higher doses (T3). It was concluded that Cd toxicity in quail had a dose dependent effect on body weight gain, blood parameters, gross and histological changes.