CLINICOPATHOLOGICAL STATUS OF MAREK’S DISEASE AT DINAJPUR DISTRICT

Abstract

The study was designed to investigate the pathological conditions of Marek’s disease in the small scale commercial layer farms at different region in Dinajpur district. Chickens are the most important natural host for Marek's disease virus, a highly cell-associated but readily transmitted alphaherpes virus with lymphotropic properties of gammaherpes viruses. The objective of the present study was to investigate the pathological features of Marek’s disease in the recent outbreaks in commercial poultry farms at dinajpur district. A total of 18 dead or sick birds were obtained from 6 different layer farms at dinajpur district with clinical suspicion of Marek’ disease, during the period from January to June 2015. On necropsy, Grossly large or military whitish nodular lesions were found in the liver, spleen & enlargement of sciatic nerve. Histologically, lymphomatous lesions of various extent and nature were observed in different organs. In the liver and spleen, the lymphomatosis was associated with extensive damage of the parenchyma were characterized by diffuse as well as focal and nodular proliferation of lymphocytes. In the period of six month, total 61 diseased birds were affected of which 18 dead or sick chickens are examined and taken sample for pathological investigation. The present study showed that overall prevalence at Dinajpur district were 0.45% whereas 0.48%, 0.53%, 0.40% 0.17% 0.78%and 0.35% in 6 farms respectively. The mortality rate 0.25% whereas 0.20%, 0.27%, 0.25%, 0.13%, 0.44 % and 0.20% The mortality was higher in nonvaccinated than in vaccinated birds. The findings of the present study would suggest that Marek’s disease can be expected its etiology, conventional and advance tools and techniques being used for its diagnosis, prevention and control strategies in poultry.