COMPARATIVE EFFECTS OF NEEM LEAVES (Azadirachta indica) SUSPENSION AND TOLTRAZURIL AGAINST COCCIDIOSIS IN SONALI CHICKEN

Abstract

Coccidiosis is recognized as the parasitic disease with the greatest economic impact on poultry industries worldwide. Sonail chicken commonly affected by coccidiosis in Bangladesh. Recently, the concerns about possible drug resistance have aroused great caution in the usage of drug in the animal industry. As one of its alternative nowadays herbal extracts are used and Neem leaves (Azadirachta indica) have anti-coccidial property. This work was conducted to evaluate the comparative efficacy of Neem leaves suspension and toltrazuril on coccidial load, blood constituents, growth performance of sonali chicken infected with Eimeria spp. The location was in Laboratory and experimental shed under the department of physiology and pharmacology, HSTU, Dinajpur, 2nd January to 3rd February, 2019. Eighty (80) sonali chicken of seven days old were randomly divided into four groups named T0, T1 T2 and T3 are each group contained 20 birds. All groups were supplied E. spp orally except T0 group and after 3 days T2 group was treated with Neem Leaves Suspension (5%) for 15 days and T3 groups was treated with toltrazuril (Coxitril ®) solution (1 ml/lit) for 2 day. Results showed that protozoal load significantly (P<0.01) decreased in T2 & T3 groups whereas significantly (P<0.01) increased in T0 and T1 group. In case of hematological parameters total erythrocyte count and hemoglobin in different treatment groups were almost similar and the differences were statistically non-significant (P>0.05) except total leukocyte count which was statistically significant (P<0.01). The body weight of T0, T1, T2 and T3 group at 0 th day were 332.65, 269.81, 269.81, 489.22 gm respectively which is statistically significant (P<0.01) and highest body weight gain was recorded from Neem Leaves Suspension treated T3 group. In conclusion, neem leaves suspension have significant effects on protozoal load, body weight and no significant effect on heamatological parameters except total leukocyte count which is statistically significant.