Masters Thesis

ANTIDIABETOGENIC IMPACT OF BITTER MELON (MOMORDICACHARANTIA) AND GARLIC (ALLIUM SATIVUM) ON ALLOXAN INDUCED DIABETIC RABBIT MODEL A Thesis By AMBIARA

Sun, 01 May 2016 00:00:00 GMT

ANTIDIABETOGENIC IMPACT OF BITTER MELON (MOMORDICACHARANTIA) AND GARLIC (ALLIUM SATIVUM) ON ALLOXAN INDUCED DIABETIC RABBIT MODEL A Thesis By AMBIARA AMBIARA The present study was undertaken to investigate the antidiabetic effect of the bitter melon and garlic on alloxan induced diabetes in experimental rabbits. After acclimatization of the age of 4 months rabbits (New Zealand white) were randomly assigned into five groups (A, B, C, D and E) and each group was remained 4 rabbits. Group A was kept for negative control (without alloxan), Group B was kept for positive control (with alloxan) treated with alloxan intramuscullarly @75mg /kg body weight, Group C was treated with bitter melon @250mg/kg body weight orally along with alloxan, Group D was treated with garlic @750mg/kg body weight orally along with alloxan, Group E treated with combined at previous doses of bitter melon and garlic along with alloxan. Over the course of the trial, observations were recorded for induction of diabetics, blood glucose level, body weight, packed cell volume, ESR and Hb (Hemoglobin) level after 72 hours of injection. Blood glucose level were increased significantly (p<0.05) in all treated groups compared to the negative control group and the highest induction was recorded in group B treated with alloxan. Body weight was decreased significantly (p<0.05) in all treated groups and lowest was recorded in group B which received treatment Alloxan. There was significant decreased in blood glucose level in all treated group C, D, E compared to the B group and lowest glucose level was recorded in E groupwhen treated with combined medicinal herbs and body weight was increased in all treated group C, D, E compared to the B group and highest was recorded in D group. PCV level was the highest in group E which was treated with both garlic and bitter melon compare to the A group. The Hb ( Hemoglobin) gm/dl concentration was the highest in group E which was treated with both garlic and bitter melon compare to the A group. The study was revealed that the Hb (Hemoglobin) gm/dl concentration was the highest in group B treated with alloxan.ESR was highest in group B treated with alloxan and lowest in group E. The present study reveals that combined II treatment with bitter melon and garlic increases body weight and decreases glucose level without affecting health of rabbits. The results of this study show that chronic oral administration of a suspension of bitter melon and garlic is an appropriate dosage may be good alternative as antidiabetic agent. A Thesis By AMBIARA Student ID. 1504014 Session: 2015-16 Semester: January-June, 2016 Submitted to the Department of Physiology & Pharmacology Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh In fulfillment of the requirements for the degree of Master of Science DEPARTMENT OF PHYSIOLOGY AND PHARMACOLOGY HAJEE MOHAMMAD DANESH SCIENCE AND TECHNOLOGY UNIVERSITY, DINAJPUR0-5200, BANGLADESH

EFFECT OF IPIL IPIL AND BEAN LEAVES SUPPLEMENTATION ON GROWTH PERFORMANCE AND EGG PRODUCTION OF JAPANESE QUAIL

Thu, 01 Dec 2016 00:00:00 GMT

EFFECT OF IPIL IPIL AND BEAN LEAVES SUPPLEMENTATION ON GROWTH PERFORMANCE AND EGG PRODUCTION OF JAPANESE QUAIL SARKAR, SUMON This study was conducted in the Department of Physiology and Pharmacology at Hajee Mohammad Danesh Science and Technology University, Dinajpur to determine the effect of Ipil ipil and bean leaves supplementation on egg production and growth performance of Japanese quail. A total of 40 “Japanese Quail” at the age of 42 days (06 weeks) old were divided into four groups named T0, T1, T2 and T3 respectively. Group T0 was considered as control which fed only with commercial layer ration. Group T1 was supplemented with formulation of 2 gm grinded Ipil Ipil leaves, Group T2 with 2 gm grinded Bean leaves and Group T3 with 2 gm grinded Ipil Ipil leaves plus 2 gm grinded Bean leaves per kg feed respectively. Observations were recorded for growth performance, egg production and egg quality of quail. Increased egg production rate was observed in Ipil Ipil supplemented groups (group T1). Body weights were increased significantly (p<0.05) in all treated groups in respect to the control and highest was recorded in combined Ipil Ipil and Bean leaves supplemented groups (Group T3). In treatment groups, there were significant increase in egg production, but in case of control group no increasement of egg production was observed. There was no significant pathological change in any internal organs of the layer of treated groups. Best result was found in the group T3. The present study reveals that combined supplementation of Ipil Ipil and Bean leaves gives better result over the other groups in respect to growth performance, egg production and egg quality. A THESIS BY SUMON SARKAR Registration No.: 1505016 Session: 2015-2016 Semester: July-December, 2016 Submitted to the Department of Physiology & Pharmacology Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh in partial fulfillment of the requirements For the degree of MASTER OF SCIENCE (MS) IN PHYSIOLOGY

EFFECTS OF FENUGREEK, ANTIBIOTIC, IGNATIA AMARA AND GINGER ON GROWTH PERFORMANCE OF JAPANESE QUAIL

Fri, 01 Jun 2018 00:00:00 GMT

EFFECTS OF FENUGREEK, ANTIBIOTIC, IGNATIA AMARA AND GINGER ON GROWTH PERFORMANCE OF JAPANESE QUAIL MOSTAKIM, MARUF-UL- Effect of fenugreek, antibiotics, ginger and ignatia on body weight, body weight gain, feed consumption and FCR of Japanese quails was evaluated in this study. Fifty Japanese quails were randomly allotted to five treatments identified as T0, T1, T2, T3 and T4. Birds on T0 served as control and T1, T2, T3 and T4 groups were treated with fenugreek, antibiotics, ginger and ignatia respectively. Fenugreek and ginger was in powder form while others were in liquid form. Average body weight in different treatments were different from the control for body weight in 1% level of significance. Feed consumption, body weight gain and feed conversion ratio in different treatments were different from the control for body weight in 5% level of significance. The birds fed the liquid form of ignatia showed better body weight, body weight gain, feed consumption and feed conversion ratio and are comparatively significant than those feed with fenugreek, antibiotics and ginger with those of control group. A THESIS BY MARUF-UL-MOSTAKIM REGISTRATION NO: 1605187 MS IN PHYSIOLOGY SEMESTER: JANUARY - JUNE, 2017 SESSION: 2016-2017 Submitted to Department of Physiology Faculty of Post Graduate Studies Hajee Mohammad Danesh Science and Technology University, Dinajpur-5200 MASTER OF SCIENCE (MS) IN PHYSIOLOGY

EFFICACY OF GUAVA LEAVES (Psidium guajava) SUSPENSION ON GROWTH, ANTIBACTERIAL AND HEMATOLOGICAL PERFORMANCES IN E. coli INOCULATED JAPANESE QUAIL

Fri, 01 Jun 2018 00:00:00 GMT

EFFICACY OF GUAVA LEAVES (Psidium guajava) SUSPENSION ON GROWTH, ANTIBACTERIAL AND HEMATOLOGICAL PERFORMANCES IN E. coli INOCULATED JAPANESE QUAIL MAHATO, KRISHNA PRASAD The present study was designed to determine the growth, antibacterial and hematological effects of guava leaf (Psidium guajava) suspension in E. coli infected Japanese quail under the Department of Physiology and Pharmacology, HSTU, Dinajpur, Bangladesh, during September to October, 2017. A total of 40 quails of 10 days old were randomly assigned into four treatment groups named T0, T1, T2, T3 and each group contained 10 birds. GroupT0 and T1 were considered as negative and positive control, respectively. Group T2and T3 were treated with guava leaf (Psidium guajava) suspension and Doxycycline respectively. At 5 days interval, live body weights were recorded, bacterial loads in feces were counted and blood parameters were determined. Mortality was also observed in different treatment groups throughout the experiment. Body weights were significantly (P<0.05) increased in T2 and T3 group compared is T0and T1where as the bacterial load counts were significantly (P<0.05) decreased in T2 and T3compared is T0 and T1 groups. The present study was revealed that the mortality rate was significantly (P<0.05) higher in T1 group. There were significant (P<0.05) variation of total leucocytes count neutrophil, lymphocyte and eosinophil among the different treatment groups. But, the eosinophil count was insignificantly (P>0.05) varied among the treatment groups on the day 22th and 32th. A THESIS BY KRISHNA PRASAD MAHATO REGISTRATION NO. 1605190 SESSION: 2016-2017 SEMESTER: JANUARY–JUNE, 2016 MASTER OF SCIENCE (MS) IN PHARMACOLOGY Submitted to the Department of Physiology & Pharmacology Hajee Mohammad Danesh Science and Technology University, Dinajpur-5200, Bangladesh. In Partial fulfillment of the requirements For the degree of MASTER OF SCIENCE (MS) IN PHARMACOLOGY